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Availability · June 26, 1998

FDA approves a computer second read of mammograms

On 26 June 1998 the FDA approved R2 Technology's ImageChecker M1000, a system that marks suspicious regions on a screening mammogram for the radiologist to review after the initial reading.

Why it matters

A program that looks for cancer on an image could be sold to clinics, but only as a second read after a person. The FDA made a further study a condition of approval: how the system would change the number of false-positive work-ups.

Approval under PMA P970058; the advisory panel met on 11 May 1998. In the applicant's prospective study 14 radiologists at 5 institutions read 23,682 cases before installation and 14,817 after; the mean work-up rate was 8.3% and 7.6%, and the FDA recorded no significant increase. In a retrospective study the system marked 17 of 21 malignant microcalcifications on prior films. The FDA documents do not call the approval the first, and the record does not claim it.

Event record

Event date
June 26, 1998
Timeline date
Event date
Verification
Sources gathered automatically · September 25, 2026
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ID
evt-0739

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