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Milestone · 1965

The DENDRAL project begins

Stanford began building a system that identifies the structure of an organic molecule from its mass spectrum, using rules supplied by chemists.

Why it matters

The field recovered results by trading general search for a narrow task filled with expert knowledge.

DENDRAL demonstrated what Feigenbaum later stated outright: a system's power comes from domain knowledge, not from the elegance of its inference mechanism. Rules were extracted from chemists in long interviews, and that labour created the separate problem of knowledge acquisition. Meta-DENDRAL later tried to derive the rules automatically.

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Event date
1965 · Approximate date
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Event date
Verification
Sources gathered automatically · September 27, 2026
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ID
evt-0104

The year 1965 follows the participants' retrospective; sources do not give a month. Lederberg's report to NASA, DENDRAL-64, is dated 15 December 1964: the notation algorithm the project grew from.

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